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Image Search Results
Journal: Oncotarget
Article Title: Upregulation of miR-572 transcriptionally suppresses SOCS1 and p21 and contributes to human ovarian cancer progression
doi:
Figure Lengend Snippet: ( A ) Analysis of a public microarray data revealed that miRNA-572 was upregulated in human ovarian cancer tissues ( n = 183) compared with normal ovarian tissues ( n = 8; P < 0.0001; NCBI/E-MTAB-1067). ( B ) Real-time PCR analysis of miR-572 expression in different clinical stages of human ovarian cancer. Transcript levels were normalized to U6 expression. The boundaries of the boxes represent the lower and upper quartiles; the lines within the boxes and whiskers denote the median and outer limits, respectively. ( C ) Kaplan-Meier analysis of overall survival for patients with ovarian cancer stratified by low miR-572 (≤ median, n = 54) and high miR-572 (> median, n = 54) expression. ( D ) Real-time PCR analysis of miR-572 expression in 12 freshly-isolated ovarian cancer tissue specimens and two normal ovarian tissue specimens. ( E ) Real-time PCR analysis of miR-572 expression in 13 ovarian cancer cell lines and a normal ovarian epithelial cell line (HOSEpiC). Transcript levels were normalized to U6 expression. Experiments were repeated at least three times with similar results; values are mean ± SD; * P < 0.05.
Article Snippet:
Techniques: Microarray, Real-time Polymerase Chain Reaction, Expressing, Isolation
Journal: International Journal of Medical Sciences
Article Title: Identification and Validation of Prognostic Markers for Endometriosis-Associated Ovarian Cancer
doi: 10.7150/ijms.97024
Figure Lengend Snippet: The expression of ADAMTS19 and TUBB in EAOC. (a) The expression levels of ADAMTS19 and TUBB were detected by RT-qPCR in the normal ovarian epithelial cell IOSE80 and the ovarian clear cell carcinoma cell ES-2, and the ovarian endometrioid carcinoma cell TOV-112D. (b) Representative images of ADAMTS19 and TUBB proteins immunohistochemical staining of ovarian tissue sections from patients in the Normal and Tumour groups, scale bar = 25 μm. (**: P <0.01, ***: P <0.001).
Article Snippet:
Techniques: Expressing, Quantitative RT-PCR, Immunohistochemical staining, Staining